Microtubules (green), their sites of nucleation (red/yellow) and nuclei (blue) are shown simultaneously throughout the hyphal cytoplasm of Allomyces macrogynus prepared using immunofluorescence methods and imaged with laser scanning confocal microscopy. Rearrangements in cytoplasmic order are typically coupled to major events of cell morphogenesis. This is evident here as the cell undergoes early stages of dichotomous branching. (Robert Roberson)